1. A 65-year-old man who is receiving unfractionated heparin following major orthopaedic surgery suffers a deep vein thrombosis and a pulmonary embolus six days post-operatively. A diagnosis of heparin-induced thrombocytopenia (HIT) is established. He has been on warfarin for one day. His platelet count is 72 _109 /l. The most appropriate management, in addition to stopping unfractionated heparin, is: a Administration of low molecular weight heparin b Commencement of argatroban c Commencement of argatroban and administration of vitamin K d Commencement of fondaparinux e Continuation of warfarin
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