1. The genesis of life is sometimes said to have required four things: energy, concentration,…

1. The genesis of life is sometimes said to have required four
things: energy, concentration, protection, and catalysis (for example, Cowen
1995). Explain why each of these four things was necessary for the generation
of the primordial form.

2. What clues in the way RNA is used in modern cells hint that
RNA may have an ancient role in cellular metabolism?

3. Briefly summarize two studies on evolution of RNA populations
in the lab. In each experiment, what

ability(ies) did the RNA population develop during evolution
(i.e., what was the change in phenotype)? Do you think these RNA

1. The genesis of life is sometimes said to have required four
things: energy, concentration, protection, and catalysis (for example, Cowen
1995). Explain why each of these four things was necessary for the generation
of the primordial form.

2. What clues in the way RNA is used in modern cells hint that
RNA may have an ancient role in cellular metabolism?

3. Briefly summarize two studies on evolution of RNA populations
in the lab. In each experiment, what

ability(ies) did the RNA population develop during evolution
(i.e., what was the change in phenotype)? Do you think these RNA populations
qualify as life? Do you think that a self-replicating RNA population will be developed
in the lab in your lifetime?

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