Solved > 31) Individuals with G6PDH deficiency have increased resistance:2010335 …

31) Individuals with G6PDH deficiency have increased resistance to malaria because the parasite does not survive well in cells with

A) anemia.

B) high levels of NADPH.

C) low levels of NADPH.

D) hexose 6-phosphate.

32) The non-oxidative stage of the pentose phosphate pathway ________.

A) produces NADPH and releases CO2

B) consists entirely of near-equilibrium reactions

C) contains two reactions whose enzymes are allosterically inhibited by NADPH

D) consumes four ATP molecules

33) The pentose phosphate pathway can alternatively be called the pentose phosphate cycle because ________ is a net product of the pathway that can be recycled.

A) glucose 6-phosphate

B) NADP+

C) carbon dioxide

D) phosphate

E) UDP

34) Deficiencies in G6PDH (glucose-6-phosphate dehydrogenase) in humans causes

A) varying degrees of hemolytic anemia.

B) increased resistance to malaria.

C) lack of NADPH in many cells.

D) All of the above.

E) A and B.

35) The major regulatory step of the pentose phosphate pathway is catalyzed by which enzyme?

A) Transaldolase.

B) Phosphofructokinase-1.

C) Glucose 6-phosphate dehydrogenase.

D) Ribose 5-phosphate isomerase.

36) The non-oxidative stage of the pentose phosphate pathway produces substances that are intermediates of ________.

A) glycolysis

B) the citric acid cycle

C) the Cori cycle

D) glycogenolysis

37) Fragments containing three carbons can be transferred from a ketose phosphate to an aldose phosphate by the enzyme ________.

A) pyruvate carboxylase

B) transaldolase

C) debranching enzyme

D) ribose-5-phosphate isomerase

38) What is the prosthetic group of transketolase?

A) Thiamine pyrophosphate.

B) Biotin.

C) Pyridoxal phosphate.

D) NAD+.

39) Which is not a function of the main products of the pentose phosphate pathway?

A) To maintain levels of NADPH.

B) To provide reducing power for the synthesis of fatty acids.

C) To serve as precursors in the biosynthesis of RNA and DNA.

D) To raise the concentration of cAMP.

40) The activity of glycogen phosphorylase can be controlled by

A) phosphorylation.

B) ATP.

C) glucose 6-phosphate.

D) protein subunit separation.

E) All of the above.

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